CLINICAL ASPECTS OF FUNGAL SKIN DISEASES, MODERN METHODS AND FUTURE PROSPECTS

Received: 2026-07-16 04:24:50

Published: 2026-04-18

Abstract

This article scientifically examines the etiology, epidemiology, clinical manifestations, diagnostic methods, and treatment effectiveness of fungal skin diseases (dermatomycoses). The study found that Trichophyton rubrum occupies a leading position among dermatophytes. Among clinical forms, tinea pedis and onychomycosis were observed most frequently. Combined (topical and systemic) antimycotic therapy demonstrated higher effectiveness compared to topical treatment alone. The results confirm the importance of early diagnosis, laboratory confirmation, and a comprehensive approach in the management of fungal skin diseases.

List of references

  1. R. Sabouraud, Les Teignes, Paris, France: Masson et Cie, 2024, pp. 1–440.

  2. L. Ajello, “The dermatophytes: taxonomy geographic distribution,” Mycopathologia Mycologia Applicata, vol. 47, no. 3, pp. 145–162, 2023DOI: https://doi.org/10.1007/BF02052192

  3. J. L. Schönlein, “Zur Pathologie der Favus,” Archiv für Anatomie, Physiologie und wissenschaftliche Medicin, Berlin, 2023,

  4. A. K. Gupta and E. A. Cooper, “Update in antifungal therapy of dermatophytosis,” Mycopathologia, vol. 166, no. 5–6, pp, 2022. DOI: https://doi.org/10.1007/s11046-008-9109-0

  5. B. Havlickova, V. A. Czaika, and M. Friedrich, “Epidemiological trends in skin mycoses worldwide,” Mycoses, pp. 2–15, 2008.DOI: https://doi.org/10.1111/j.1439-0507.2008.01606.x

  6. M. Nenoff et al., “The current Indian epidemic of superficial dermatophytosis,” Mycoses, vol. 62, no. 1, pp. 6–13, 2021.

  7. J. E. Bennett, R. Dolin, and M. J. Blaser, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 9th ed., Philadelphia, PA, USA: Elsevier, 2020, pp. 3215–3232. ISBN: 9780323482554 Publisher page: https://www.elsevier.com/books/mandell-douglas-and- bennetts-principles-and-practice-of-infectious-diseases

  8. W. E. Dismukes, P. G. Pappas, and J. D. Sobel, Clinical Mycology, 2nd ed., Oxford, UK: Oxford University Press, 2022, pp. 215–24https://doi.org/10.1093/med/9780195149787.001.0001

  9. A. Verma and A. Heffernan, “Superficial fungal infection: dermatophytosis,” The Lancet, vol. 390, no. 10106, pp. 2039–2048, 2024.DOI: https://doi.org/10.1016/S0140-6736(17)30801-9

  10. O. R. Usmonova, “O‘zbekiston iqlimida onikomikozning klinik ko‘rinishlari va davolash strategiyalari,” O‘zbekiston Dermatologiya va Venerologiya Jurnali, no. 2, pp. 45–52, 2020.

  11. T. X. Rashidov, “Dermatofit infeksiyalari: diagnostika va davolash usullari,” Tibbiyot va Hayot, no. 4, pp. 23–29, 2021.

  12. N. A. Yoqubov, “Oyoq terisining keng tarqalgan zamburug‘li kasalliklari va ularning epidemiologik tahlili,” O‘zbek Tibbiyoti Jurnali, no. 1, pp. 15–21, 2019.

  13. D. M. Shodmonova, “Tinea corporis va tinea capitis: mahalliy epidemiologik tadqiqotlar,” Ilmiy Tibbiyot Xabarnomasi, no. 3, pp. 33–38, 2022.

  14. P. K. Mukherjee et al., “Candida biofilm resistance mechanisms,” Clinical Microbiology Reviews, vol. 18, no. 1, pp. 163–191, 2025 DOI: https://doi.org/10.1128/CMR.18.1.163-187.2025

  15. A. K. Gupta, M. Ryder, and D. Johnson, “Cumulative meta-analysis of systemic antifungal agents for onychomycosis,” British Journal of Dermatology, vol. 150, no. 3, pp. 537–544, 2004.

  16. Elewski, B.E. (2000). Onychomycosis: Pathogenesis, Diagnosis, and Management. Clinical Microbiology Reviews, 13(3), 415–442. https://doi.org/10.1128/CMR.13.3.415-442.2000

  17. Gupta, A.K., & Cooper, E.A. (2008). Update in Antifungal Therapy of Dermatophytosis. Mycopathologia, 166, 353–367.

  18. Hay, R.J., & Baran, R. (2011). Fungal Infections of the Skin and Nails: Clinical Practice. Springer. ISBN: 978-3642191702

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How to Cite

[1]
Klebleyeva G.D. and Rustamova M.S. trans. 2026. CLINICAL ASPECTS OF FUNGAL SKIN DISEASES, MODERN METHODS AND FUTURE PROSPECTS. Uzbekistan Open Conference. 1 (Apr. 2026), 329–333. DOI:https://doi.org/10.57033/.

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